Molecule record

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine

C₂₂H₂₄BrFN₄O₂

475.36 g/mol

Loading structure

Molecular properties

Formula: C₂₂H₂₄BrFN₄O₂
Molar mass: 475.36 g·mol⁻¹
Exact mass: 474.1067 Da
: 12
PubChem CID: 3081361

Functional groups

Alkane / alkyl carbon

Aromatic ring

Aryl halide

Ether

Secondary amine

Tertiary amine

Physical properties

No source-backed physical properties are curated for this molecule yet.

Common names and synonyms

4-Quninazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
443913-73-3
AZD-6474
AZD6474
C22H24BrFN4O2
CHEBI:49960
Caprelsa
DTXCID9026681

Show all 24 synonyms

DTXSID1046681
GNF-PF-2188
L01XE12
MFCD07772346
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine
NSC-744325
NSC-760766
RefChem:58965
Vandetanib
YO460OQ37K
ZD-64
ZD-6474
ZD6474
Zactima
vandetanib (zd6474)
vandetanibum

Structure identifiers

Canonical SMILES: COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1
Isomeric SMILES: CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC
InChI: InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
InChIKey: UHTHHESEBZOYNR-UHFFFAOYSA-N
PubChem CID: 3081361

Spectroscopy

Tabs appear only for spectra stored with clear provenance.

Open library

No redistributable or simulated spectroscopy record is attached yet.

Simulated NMR

On-demand educational prediction for N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine; not experimental data.

Simulated EI mass spectrum

On-demand educational fragmentation for N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine; not experimental data.

Sources

Molecule identity

Retrieved 8/20/2026. Reuse status is summarized by the badge; open the source for full details.

PubChem(link only)

Open source record